If you’ve been researching ways to change your relationship with alcohol, you’ve probably come across two names pretty quickly: naltrexone and acamprosate. At first glance, they can seem interchangeable. Both are meant to help people drink differently. But they’re actually designed for very different situations.
There’s nothing that officially says you can’t combine a GLP-1 and alcohol, in other words, drinking while taking a medicine like Ozempic. But there are
Yes—Ozempic can reduce alcohol cravings. For some people, it’s subtle. For others, it’s hard to miss. What’s interesting isn’t just that drinking goes down. It’s how it happens. People don’t usually describe trying harder or setting stricter rules. It’s more like the interest just…drops off. A drink sounds good in theory, then halfway through, it doesn’t really land the same way.
Alcohol absolutely affects blood sugar. That part is real. What’s less obvious is how inconsistent it can feel in your body. Here’s how alcohol is actually impacting your blood sugar, in the long term and the short term.
Yes, alcohol can lower testosterone. That part isn’t really up for debate. But the nuances of its effects—and how to turn things around if you’re feeling unwell—are worth exploring.
You’ve probably heard some version of this phenomenon by now: people take Ozempic (or another GLP-1) and suddenly lose interest in alcohol. It gets framed as a kind of side-effect miracle—weight loss, fewer cravings, maybe even less desire to drink. There’s truth in that. But there are also important nuances to consider.
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About Sunnyside
Sunnyside is a comprehensive platform for building a healthier relationship with alcohol. We combine a behavior-change app, real human coaching, and Sunnyside Med — our Telehealth service where licensed providers can prescribe medication to help reduce alcohol cravings. Members using the Sunnyside app report an average 33% reduction in weekly alcohol consumption, and Sunnyside Med customers are reducing their drinking by nearly 50% on average — along with improved sleep, better mental clarity, and an overall improved sense of well-being.
What is Naltrexone? Naltrexone is a medication that works by blocking opioid receptors in the brain, which reduces the pleasurable effects of alcohol and helps decrease cravings. Originally approved by the FDA in 1994 for the treatment of alcohol dependence, Naltrexone has been shown in clinical studies to significantly reduce heavy drinking days and support long-term moderation. Sunnyside Med prescribes a compounded oral formulation containing Naltrexone as part of a comprehensive treatment plan that includes coaching, tracking, and ongoing medical support.
Sunnyside Med connects you with licensed medical providers who can prescribe compounded medication containing Naltrexone, an active ingredient that is FDA-approved to support alcohol moderation, through a private Telehealth process. Sunnyside Med is not a substitute for emergency services or inpatient treatment. If you are in crisis or experiencing severe withdrawal symptoms, please contact SAMHSA’s National Helpline at 1-800-662-4357 or call 911. We are proud partners of Moderation Management, a non-profit dedicated to reducing the harm caused by the misuse of alcohol.
Alcohol Moderation guides