Can You Drink Alcohol While Taking Creatine? What the Research Says
Yes, you can drink alcohol while taking creatine. There's no evidence that alcohol cancels out creatine's benefits, although...
If you’ve ever developed a migraine after a glass of wine, you might have assumed the alcohol was responsible. But what if you’ve had that same glass of wine dozens of other times without a problem?
Alcohol is one of the most commonly reported migraine triggers, yet the relationship isn’t as straightforward as you might expect. Some people consistently experience migraines after drinking, while others notice no connection at all. Even among people who identify alcohol as a trigger, an attack doesn’t necessarily follow every drink.
Researchers are still working to understand why. Here’s what we know about alcohol and migraines, including whether particular drinks may be more likely to cause problems, how quickly symptoms can appear, and what you can do if you suspect drinking is contributing to your attacks.
Migraine is a neurological condition involving changes in how the brain processes pain and sensory information. Although alcohol is a commonly reported trigger, researchers haven’t established exactly why it seems to provoke attacks in some people but not others.
Part of the difficulty is that migraine attacks rarely happen in isolation from everything else going on in your life. Sleep, stress, eating habits, and other factors may influence your susceptibility to an attack just as much as alcohol does.
A 2019 study surveyed 2,197 people with migraine and found that 35.6% identified alcohol as a trigger. Red wine was the beverage most frequently blamed, but only 8.8% of respondents reported that red wine triggered an attack every time they drank it.
People may associate alcohol with their migraines without experiencing an attack consistently, and those who believe alcohol is a trigger may avoid drinking altogether. Both factors make the relationship difficult to study.
A 2020 systematic review also identified alcohol as a frequently reported dietary migraine trigger. However, much of the available evidence came from surveys and observational studies, which cannot reliably establish whether alcohol actually caused an attack.
Other research has produced less convincing evidence of a connection. In a 2022 study, researchers followed 487 adults with episodic migraine for 90 days. They found no significant increase in migraine attacks during the 24 hours after participants consumed alcohol.
That doesn’t mean alcohol can’t trigger migraines. Most participants drank relatively small amounts, and the findings don’t necessarily apply to people who drink more heavily or are particularly sensitive to alcohol. They do suggest that alcohol isn’t a predictable trigger for everyone with migraine.
Researchers have suggested that migraine attacks may depend on a changing threshold of susceptibility. On a day when you’ve slept poorly, skipped a meal, or experienced significant stress, you may be more vulnerable to an attack than you would be under different circumstances.
Alcohol could contribute to that combination without being enough to trigger a migraine on its own.
This is one reason the American Migraine Foundation recommends keeping a headache diary rather than automatically eliminating every food or drink you suspect might be a trigger. Tracking what happens before an attack can help you identify recurring patterns and distinguish possible triggers from coincidences.
If you wake up with a pounding headache after drinking, how can you tell whether it’s a migraine or a hangover?
The symptoms can overlap, but they are different conditions.
Unfortunately, the distinction isn’t always obvious. Hangover headaches can involve throbbing pain and sensitivity to light or sound, both of which are also common with migraine. And if you already experience migraines, drinking may contribute to an attack that occurs alongside other hangover symptoms.
One useful clue is whether the headache resembles your usual migraine attacks. If the pain comes with familiar symptoms, such as nausea or sensitivity to light, migraine may be involved. But symptoms alone aren’t always enough to distinguish the two, particularly if your headaches are changing or becoming more frequent.
An alcohol-related headache can begin while you’re still drinking or several hours later. However, the medical classifications for alcohol-induced headaches aren’t quite the same as those for migraine attacks.
The International Classification of Headache Disorders recognizes two types of alcohol-induced headache:
These are classifications of headaches attributed to alcohol, not separate types of migraine.
Migraine attacks associated with drinking don’t necessarily follow those exact timelines. In the 2019 survey of people with migraine, nearly 90% of respondents who identified alcohol as a trigger and provided timing information reported that their attacks began within 10 hours of drinking.
That means you might feel fine after a drink in the evening but develop migraine symptoms overnight or the following morning.
Of course, timing doesn’t prove that alcohol caused the attack. Poor sleep, dehydration, missed meals, and other factors may also contribute to a headache after drinking.
Red wine has a particularly strong reputation for triggering migraines. In the 2019 survey, it was the alcoholic beverage most frequently identified as a trigger, although most people who reported a connection didn’t experience an attack every time they drank it.
But what about white wine, beer, or liquor? Is one type of alcohol less likely to cause migraines than another? Unfortunately, the research doesn’t provide a clear ranking. Alcoholic beverages contain different compounds in addition to ethanol, including substances produced during fermentation. Some of these compounds may contribute to headaches or other symptoms, but there isn’t enough evidence to identify a universally migraine-friendly alcoholic drink.
Individual responses also vary. You might notice that red wine consistently precedes your migraines while another beverage doesn’t seem to cause problems. That pattern is useful to know, but it doesn’t guarantee that the second beverage will never contribute to an attack.
Migraine is also different from symptoms brought on by alcohol intolerance. If drinking causes flushing, a rapid heartbeat, nasal congestion, or nausea alongside a headache, alcohol intolerance or another reaction may be involved. A clinician can help determine what’s causing your symptoms.
The amount you drink may influence your likelihood of developing a migraine, but alcohol isn’t the only factor worth considering. Drinking can also affect your sleep and hydration, both of which may contribute to headaches.
There’s some evidence that heavier drinking is associated with a greater likelihood of headaches among people with migraine.
In a prospective study of 98 adults with episodic migraine, researchers found that consuming five or more alcoholic drinks was associated with approximately twice the odds of a headache the following day. Drinking one or two servings wasn’t associated with a significant increase in next-day headache risk.
That doesn’t mean one or two drinks are necessarily safe for someone with migraine. The study was relatively small, and participants generally consumed modest amounts of alcohol. Someone who is particularly sensitive to alcohol might experience an attack after a single drink.
Still, the findings suggest that how much you drink may matter, even if there’s no universal threshold at which alcohol begins to trigger migraines.
Alcohol can make you feel sleepy initially, but it often interferes with sleep quality later in the night. You may wake up more frequently or find yourself awake earlier than usual, even if you fell asleep without difficulty. Our guide to alcohol and sleep explains these effects in more detail.
Poor sleep is also associated with migraine attacks. In a six-week study of 98 adults with episodic migraine, participants who reported lower sleep efficiency had a 39% greater likelihood of experiencing a headache two days later.
The study didn’t examine alcohol as a cause of poor sleep, so it doesn’t establish that alcohol-related sleep disruption leads to migraines. However, it does illustrate why sleep is worth tracking alongside alcohol consumption when you’re trying to identify possible triggers.
Alcohol increases urine production, which can contribute to dehydration. According to the National Institute on Alcohol Abuse and Alcoholism, even mild dehydration may contribute to common hangover symptoms, including thirst, fatigue, and headache.
The connection between dehydration and migraine is less straightforward. Although some people report dehydration as a migraine trigger, not every headache after drinking is caused by fluid loss.
Drinking water before, during, and after alcohol consumption can help you stay hydrated, but it won’t necessarily prevent a migraine or hangover. Alcohol affects the body in several ways, and hydration addresses only one potential contributor.
If you consistently experience migraines after drinking, reducing or avoiding alcohol may help. You don’t necessarily need to figure out exactly why alcohol affects you before making a change.
One option is to try an alcohol-free period while continuing to track your headaches. Compare the frequency and severity of your migraines with your usual pattern, keeping in mind that sleep, stress, and other factors may also influence your symptoms.
Important: If you drink heavily or regularly, have experienced alcohol withdrawal symptoms before, or aren’t sure whether it’s safe to stop, speak with a clinician first. Alcohol withdrawal can be dangerous, and some people need medical supervision when reducing or stopping alcohol.
If you’d rather cut back than stop completely, a few practical strategies may help:
Keep following the migraine treatment plan recommended by your clinician, too. Don’t assume that an over-the-counter pain reliever is safe to take after drinking, particularly if you’re taking other medications. A clinician or pharmacist can help you understand potential interactions.
If your migraines continue despite drinking less, become more frequent, or interfere with daily life, it’s worth discussing your symptoms with a healthcare professional. Alcohol may be one contributing factor, but migraine often requires its own treatment.
Most headaches after drinking aren’t medical emergencies, but certain symptoms need immediate attention.
Seek emergency care if you experience:
These symptoms can sometimes indicate conditions more serious than migraine or a hangover. The American Migraine Foundation provides additional guidance on when headache symptoms warrant emergency evaluation.
For less urgent concerns, make an appointment with your clinician if your headaches are becoming more frequent, your usual migraine treatment is no longer effective, or you’re having trouble determining what’s causing your symptoms.
If alcohol seems to contribute to your migraines, changing your drinking habits may be one way to reduce your exposure to a potential trigger. But cutting back isn’t always as simple as deciding to have fewer drinks.
Sunnyside Med is a 100% online program that combines medication, clinical care, and behavioral support to help eligible adults drink less or quit alcohol.
After completing an online assessment, you’ll meet with a licensed clinician who will review your health history and determine whether naltrexone is appropriate for you. Eligible members may receive compounded naltrexone with vitamin B6, a combination used by Sunnyside Med to support alcohol reduction.
Naltrexone works by blocking opioid receptors involved in alcohol’s rewarding effects, which can help reduce cravings and make it easier for some people to change their drinking habits. Although naltrexone is FDA-approved for alcohol dependence, Sunnyside Med’s compounded medication is not FDA-approved.
Medication is only part of the program. Sunnyside Med also includes drink tracking, personalized planning, unlimited one-on-one clinical support, human coaching, and a community of people working toward similar goals. These tools can help you recognize drinking patterns and make changes that fit your life.
In fact, 78% of active Sunnyside Med members achieved a meaningful reduction in drinking over 12 weeks. Individual results vary.
Sunnyside Med doesn’t treat or prevent migraines. However, if alcohol is one of your triggers, reducing your drinking may help you avoid some alcohol-related attacks while you continue managing migraine with your healthcare provider.
Ready to change your relationship with alcohol? Complete the brief online assessment to see whether Sunnyside Med could be a good fit.
This content is for educational purposes and isn’t a substitute for medical advice. Naltrexone is a prescription medication, and a licensed clinician determines whether it’s appropriate for each individual.
Alcohol is not a recommended treatment for migraines. Even if drinking temporarily changes how you experience pain, alcohol can disrupt sleep, contribute to dehydration, and interact with certain medications. If you experience migraines, it's best to follow the treatment plan recommended by your healthcare provider rather than using alcohol for relief.
It depends on the medication, how much you've consumed, and your health history. Some migraine medications and over-the-counter pain relievers can interact with alcohol or increase the risk of side effects. Ask your clinician or pharmacist about your specific medication rather than assuming it's safe to take after drinking.
Yes. Headaches are a possible symptom of alcohol withdrawal, along with anxiety, sweating, nausea, and tremors. Severe withdrawal can also cause seizures, hallucinations, and delirium. If you drink heavily or regularly or have experienced withdrawal symptoms before, seek medical guidance before abruptly reducing or stopping alcohol.
Yes. Migraine aura can occur without a headache, whether or not you've consumed alcohol. Aura can involve visual disturbances, tingling, or difficulty speaking. However, new or unusual neurological symptoms shouldn't automatically be attributed to migraine, particularly if they begin suddenly. Seek prompt medical evaluation.
Try tracking your drinking and headache symptoms consistently for several weeks, including days when you don't drink. Record the amount and type of alcohol, headache timing, and other possible contributing factors. There isn't a universal tracking period, but a clinician can help you review the results and determine whether a pattern is emerging.
No. Naltrexone is used to help some people reduce or stop drinking, but it doesn't treat or prevent migraines. If alcohol contributes to your attacks, drinking less may help you avoid that particular trigger. You'll still need appropriate migraine care from your healthcare provider.
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